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Drug ReportsPenicillin g procaine
Penicillin g procaine
Bicillin C-r, Penicillin G Procaine (penicillin g procaine) is a small molecule pharmaceutical. Penicillin g procaine was first approved as Bicillin c-r on 1982-01-01. It is used to treat actinomycosis, anthrax, bacterial infections, bacterial skin diseases, and botulism amongst others in the USA.
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Variants
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Commercial
Therapeutic Areas
Therapeutic Area
MeSH
infectionsD007239
respiratory tract diseasesD012140
nervous system diseasesD009422
urogenital diseasesD000091642
cardiovascular diseasesD002318
skin and connective tissue diseasesD017437
animal diseasesD000820
signs and symptoms pathological conditionsD013568
chemically-induced disordersD064419
Trade Name
FDA
EMA
Combinations
Bicillin c-r
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Penicillin g benzathine
+
Penicillin g procaine
Tradename
Company
Number
Date
Products
BICILLIN C-RKing PharmaceuticalsN-050138 RX1982-01-01
1 products, RLD, RS
BICILLIN C-R 900/300King PharmaceuticalsN-050138 RX1982-01-01
1 products, RLD, RS
Show 1 discontinued
Labels
FDA
EMA
Brand Name
Status
Last Update
bicillin c-r 900/300New Drug Application2023-10-13
bicillin crNew Drug Application2023-10-13
pfizerpenANDA2023-12-15
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
No data
HCPCS
Code
Description
J0558
Injection, penicillin g benzathine and penicillin g procaine, 100,000 units
J2510
Injection, penicillin g procaine, aqueous, up to 600,000 units
Clinical
Clinical Trials
68 clinical trials
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Indications Phases 4
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
SyphilisD013587EFO_0007504A53.91345113
PneumoniaD011014EFO_000310613126
YawsD015001EFO_0007548A66213
BacteremiaD016470EFO_0003033R78.8122
InfectionsD007239EFO_0000544112
Chronic obstructive pulmonary diseaseD029424EFO_0000341J44.911
NeutropeniaD009503D7011
NeoplasmsD009369C8011
FeverD005334HP_0001945R50.911
Staphylococcus aureusD013211NCBITaxon_128011
Show 1 more
Indications Phases 3
Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Rheumatic heart diseaseD012214EFO_1001161I09.9224
PsoriasisD011565EFO_0000676L40112
Covid-19D000086382U07.111
Heart diseasesD006331EFO_0003777I51.911
Indications Phases 1
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Healthy volunteers/patients22
OsteomyelitisD010019EFO_0003102M8611
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common namePenicillin g procaine
INN
Description
Procaine benzylpenicillin also known as penicillin G procaine, is an antibiotic useful for the treatment of a number of bacterial infections. Specifically it is used for syphilis, anthrax, mouth infections, pneumonia, diphtheria, cellulitis, and animal bites. It is given by injection into a muscle.
Classification
Small molecule
Drug classlocal anesthetics; penicillins
Image (chem structure or protein)Loading
Structure (InChI/SMILES or Protein Sequence)
CC1(C)S[C@@H]2[C@H](NC(=O)Cc3ccccc3)C(=O)N2[C@H]1C(=O)O.CCN(CC)CCOC(=O)c1ccc(N)cc1.O
Identifiers
PDB
CAS-ID54-35-3
RxCUI
ChEMBL IDCHEMBL1200936
ChEBI ID
PubChem CID5903
DrugBank
UNII ID
Target
No data
Variants
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 3,994 documents
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Safety
Black-box Warning
Black-box warning for: Bicillin c-r 900/300, Bicillin cr
Adverse Events
Top Adverse Reactions
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455 adverse events reported
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